【摘 要】
：
Antibodies against native glycosylated myelin-oligodendroc- yte-glycoprotein (MOG) were measured by ELISA in patients with multiple scler osis (MS) and controls
【机 构】
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Department of General Neurology Hertie Inst. for Clin. Brain Res. University of Tbingen H oppe-Sey
【出 处】
：
世界核心医学期刊文摘(神经病学分册)
论文部分内容阅读
Antibodies against native glycosylated myelin-oligodendroc- yte-glycoprotein (MOG) were measured by ELISA in patients with multiple scler osis (MS) and controls. Anti-MOG IgM antibodies were elevated during the first demyelinating event.Higher MOG-specific IgG antibodies were found in patients d uring relapses and in secondary chronic progressive MS compared to patients in r emission and healthy controls. Antibodies against native MOG may be a potential biomarker for MS.
Antibodies against native glycosylated myelin-oligodendrocyte-glycoprotein (MOG) were measured by ELISA in patients with multiple sclerosis (MS) and controls. Anti-MOG IgM antibodies were elevated during the first demyelinating event. Hidher MOG-specific IgG antibodies were found in patients d uring relapses and in secondary chronic progressive MS compared to patients in r emission and healthy controls. Antibodies against native MOG may be a potential biomarker for MS.
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