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目的探讨原发性肝细胞性肝癌(HCC)介入治疗后16层螺旋CT表现与血清甲胎蛋白(AFP)含量变化的关系。方法对42例HCC患者,均行经导管肝动脉化疗栓塞术(TACE),术后3～4周行上腹部平扫及双期增强扫描,观察碘油沉积范围和肿瘤强化范围,并同时测定患者血清AFP水平并计算治疗前后其下降百分率,使用统计软件分析两者的相关性。结果42例HCC患者TACE术后,肿瘤强化范围0%～100%不等,其中<25%5例,25%～50%15例,>50%22例,与患者血清AFP含量下降百分率呈负相关(r=-0.776,P<0.05)。碘油沉积范围0%～100%不等,其中无碘油沉积4例,<25%12例,25%～50%16例,>50%10例,与血清AFP含量下降百分率呈正相关(r=0.907,P<0.05)。结论HCC患者TACE后16层螺旋CT表现与血清AFP含量下降百分率具相关性,可以作为介入治疗效果的评价指标。
Objective To investigate the relationship between 16-slice spiral CT findings and serum AFP levels after interventional treatment of primary hepatocellular carcinoma (HCC). Methods Forty-two patients with HCC underwent transcatheter arterial chemoembolization (TACE). Three to four weeks after operation, upper abdominal plain and double-phase enhanced scanning were performed to observe the extent of lipiodol deposition and the extent of tumor enhancement. Patients with HCC Serum AFP levels and calculate the percentage of decline before and after treatment, using statistical software to analyze the correlation between the two. Results Forty-two patients with HCC had T 0 ranging from 0% to 100% after TACE. Among them, 25% were in 5 cases, 25% -50% in 15 cases and> 50% in 22 cases. The percentage of serum AFP in patients with HCC was negative (R = -0.776, P <0.05). The lipiodol deposition ranged from 0% to 100%. There were 4 cases without lipiodol deposition, 12 cases were <25%, 16 cases were 25% -50% and 10 cases were> 50%, which was positively correlated with the decreasing percentage of AFP in serum = 0.907, P <0.05). Conclusion The 16-slice spiral CT findings of TCC patients with HCC have a correlation with the decrease of serum AFP levels, which can be used as an evaluation index of interventional treatment.