医学上应用冷冻治疗疾病,已不是一项新颖的方法。早在1851年就已有用盐冰混合液(-20℃)治疗肿瘤的报导。十九世纪未,White开始用二氧化碳雪(-80℃)作为致冷物质治疗皮肤良性肿瘤,由于致冷温度不够,透入较浅,坏死深度不够,效果不理想,因而冷冻疗法一度处于停顿状态。1950年自液氮(-195.8℃)问 The medical application of cryotherapy for disease is no longer a novel method. As early as 1851 there have been reports of tumors treated with salt-ice mixture (-20 ° C). In the 19th century, White began to treat benign tumors of the skin with carbon dioxide snow (-80 ℃) as a cooling substance. Due to insufficient cooling temperature, insufficient penetration, insufficient depth of necrosis, and ineffective cryotherapy, the cryotherapy was at a standstill . 1950 from liquid nitrogen (-195.8 ℃) asked