论文部分内容阅读
目的分析代谢综合征(MS)患者腹部脂肪分布及与心血管损害的关系。方法108例住院患者分为MS组(70例),高血压组(EH,22例),2型糖尿病组(T2DM,16例),计算三组腹内脂肪面积(VA)、腹壁脂肪面积(SA)及VA/SA,并分析它们与左室重量(LVM)、左室重量指数(LVMI)、颈动脉内膜中层厚度(IMT)、心肌缺血的关系。结果MS组患者较EH组和T2DM组VA显著增高(115·69±48·72cm2vs69·96±25·41cm2、55·96±29·75cm2,P均<0·01),VA≥80cm2组较VA<80cm2组LVM、LVMI均明显升高(186±70gvs155±44g,51±17g/m2vs44±13g/m2,P均<0·05),VA/SA≥0·75组较VA/SA<0·75组左、右侧IMT均明显增厚(0·90±0·41mmvs0·75±0·21mm,0·89±0·32mmvs0·77±0·21mm,P均<0·05),VA≥100cm2组心肌缺血率和缺血程度明显高于VA<100cm2组(P<0·05)。收缩压、舒张压、VA导致IMT增厚的OR值有显著意义。结论代谢综合征时腹内脂肪明显堆积,其堆积的程度与心血管损害的程度密切相关,且腹内脂肪是心血管损害的独立影响因素。
Objective To analyze the distribution of abdominal fat in patients with metabolic syndrome (MS) and its relationship with cardiovascular damage. Methods A total of 108 hospitalized patients were divided into MS group (70 cases), hypertension group (EH group, 22 cases) and T2DM group (16 cases). The intra-abdominal fat area (VA), abdominal fat area SA) and VA / SA, and analyzed their relationship with left ventricular mass (LVM), left ventricular mass index (LVMI), carotid artery intima-media thickness (IMT) and myocardial ischemia. Results Compared with EH group and T2DM group, VA in MS group was significantly higher than that in VA group (115.69 ± 48.72 cm 2 vs 69.96 ± 25.41 cm 2, 55.96 ± 29.75 cm 2, P <0.01) The LVM and LVMI of <80cm2 group were significantly higher than those of VA / SA ≥0 · 75 group (186 ± 70gvs155 ± 44g, 51 ± 17g / m2vs44 ± 13g / m2, P < The left and right IMT of 75 groups were significantly thicker (0.90 ± 0.41mmvs0 · 75 ± 0.21mm, 0.89 ± 0.32mmvs0 · 77 ± 0.21mm, P <0.05), VA≥ The rate of myocardial ischemia and the degree of ischemia in 100cm2 group were significantly higher than those in VA <100cm2 group (P <0.05). Systolic blood pressure, diastolic blood pressure, VA lead to IMT thickening of the OR value is significant. Conclusion Metabolic syndrome significantly accumulates intra-abdominal fat, which is closely related to the degree of cardiovascular damage. Intra-abdominal fat is an independent factor of cardiovascular damage.