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目的掌握新疆吸毒人群及配偶连续3年的感染状况,估计全疆两类人群HIV-1新发感染率。方法对2009-2011年新疆10个艾滋病高流行或潜在高流行地区吸毒及配偶的737份HIV阳性样本应用HIV-1BED ELA方法估计人群HIV-1新发感染率。结果全疆两类人群连续3年7 699份样本检出HIV-1阳性标本1 188份,其中剔除既往感染者451份,737份符合BED检测标准,105份被判为新发感染。吸毒人群HIV-1新发感染率3年分别为7.39%(95%CI 2.56,12.22)、3.94%(95%CI 2.59,5.28)、3.86%(95%CI 2.46,5.27),配偶人群新发感染率分别为4.92%(95%CI 2.25,7.59)、2.59%(95%CI 1.18,4.00)、1.79%(95%CI 0.55,3.03)。结论 3年HIV-1新发感染率呈下降趋势,但艾滋病防治力度不能松懈,否则吸毒向配偶及普通人群二代传播更难控制。
Objective To understand the infection status of drug addicts and spouses in Xinjiang for three consecutive years and estimate the prevalence of HIV-1 infection in two populations in Xinjiang. Methods HIV-1BED ELA method was used to estimate the prevalence of HIV-1 infection in 737 HIV-positive samples of drug addicts and spouses in 10 AIDS-endemic areas or potential high-prevalence areas in Xinjiang from 2009 to 2011. Results A total of 1 188 HIV-1 positive samples were detected in 7 699 samples of Xinjiang people in three consecutive years. Among them, 451 were excluded from previous infection, 737 were eligible for BED, and 105 were newly diagnosed. The rates of new HIV-1 infection among drug users were 7.39% (95% CI 2.56, 12.22), 3.94% (95% CI 2.59, 5.28), 3.86% (95% CI 2.46, 5.27) The infection rates were 4.92% (95% CI 2.25, 7.59), 2.59% (95% CI 1.18, 4.00) and 1.79% (95% CI 0.55, 3.03) respectively. Conclusions The incidence of new HIV-1 infection in three years shows a declining trend, but the prevention and treatment of AIDS can not be relaxed. Otherwise, it is more difficult to control the spread of HIV to spouses and the general population.