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在乙型病毒性肝炎(HB)高发区如东南亚,乙型肝炎病毒(HBV)的围产期传播是 HBV 感染高发的重要因素。乙型肝炎表面抗原/乙型抗原e 抗原(HBsAg/HBeAg)阳性母亲的新生儿中70～90%成为慢性携带者。围产期传播途径有三:①宫内经胎盘传播(产前传播);②产时传播;③产后经母乳喂养或抚养过程传播。大多数专家认为围产期传播主要发生在产时,但尚未明确其机理。HBV 的传播或是由于胎盘的创面母血渗入而污染分娩伤口所致,及/或
Perinatal transmission of hepatitis B virus (HBV) is an important factor in the high incidence of HBV infection in high incidence areas of hepatitis B (HB) such as Southeast Asia. 70-90% of newborns with hepatitis B surface antigen / type B e antigen (HBsAg / HBeAg) positive mothers become chronic carriers. There are three ways of perinatal transmission: ① intrauterine transmission through the placenta (prenatal transmission); ② intrapartum transmission; ③ postpartum breastfeeding or raising process of transmission. Most experts believe that perinatal transmission occurs mainly during labor hours, but its mechanism has not yet been clarified. The spread of HBV is caused by contaminated birthing wounds due to infiltration of the mother’s blood from the placenta and / or