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目的探讨小儿PDA经皮心导管介入封堵术的疗效。方法对采取经皮心导管介入封堵术治疗PDA患儿86例的临床资料进行总结,观察术后并发症发生情况,并对比封堵前后肺动脉收缩压、舒张压及平均压变化,以及经皮心导管介入封堵术治疗PDA的成功率,以评价经皮心导管介入封堵术治疗PDA的疗效。结果 86例患儿采取经皮心导管介入封堵术治疗,封堵后经造影或超声心动图检查,少量残余分流4例(占4.65%),微量残余分流10例(占11.62%);完全封堵72例(占83.72%);术后24 h超声心动图检查封堵成功86例,封堵成功率为100%。封堵后86例患儿肺动脉收缩压、舒张压和平均压[(4.64±2.16)kPa、(1.39±1.09)kPa、(2.83±1.59)kPa]较封堵前[(6.87±3.23)kPa、(2.64±2.17)kPa、(4.71±2.76)kPa]均显著下降,差异均有统计学意义(Pa<0.05)。结论应用经皮心导管介入封堵方法治疗小儿PDA疗效肯定,具有创伤小,恢复快,并发症发生率低的特点。
Objective To investigate the curative effect of transcatheter closure of PDA in children. Methods The clinical data of 86 cases treated with transcatheter closure of percutaneous cardiac catheterization were summarized and the postoperative complications were observed. The changes of pulmonary artery systolic pressure, diastolic pressure and mean pressure before and after occlusion were compared, The success rate of cardiac catheterization and closure in the treatment of PDA to evaluate the efficacy of transcatheter closure of percutaneous cardiac catheterization in the treatment of PDA. Results 86 cases were treated by transcatheter closure of percutaneous transcatheter arterial catheterization. After occlusion, 4 cases (4.65%) had residual residual shunt and 10 cases (11.62%) had residual residual shunt after closure. Seventy-two cases were occluded (83.72%). Seventy-six cases were successfully echocardiographed at 24 hours after operation. The success rate of occlusion was 100%. After closure, the systolic pressure, diastolic pressure and mean pressure of pulmonary artery in 86 children ([4.64 ± 2.16] kPa, (1.39 ± 1.09) kPa, (2.83 ± 1.59) kPa] (2.64 ± 2.17) kPa, (4.71 ± 2.76) kPa], all of which were statistically significant (Pa <0.05). Conclusion The percutaneous cardiac catheterization method is effective in treating pediatric PDA with small trauma, fast recovery and low complication rate.