为探讨偏头痛与β内啡肽(βEP) 的关系,本文用放射免疫分析法(RIA) 测定30 例偏头痛患者血浆和脑脊液βEP 的含量变化,发现典型偏头痛和普通型偏头痛以及偏头痛各期βEP含量均明显降低,提示βEP 减少是偏头痛的发病机理之一。认为两型偏头痛发病机理相同,间隙期存在鸦片肽功能紊乱,当βEP 减少到一定程度偏头痛发作 In order to investigate the relationship between migraine and β-endorphin (β-EP), radioimmunoassay (RIA) was used to detect the content of βEP in plasma and cerebrospinal fluid in 30 migraineurs. The results showed that typical migraine and common type Migraine and migraine phases of β  EP content were significantly lower, suggesting that β  EP reduction is one of the pathogenesis of migraine. That the two types of migraine the same pathogenesis, the existence of gap opioid peptide dysfunction, when β  EP reduced to some extent migraine attacks