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目的回顾性分析下肢动脉硬化性闭塞症(arteriosclerosis obliterans,ASO)介入治疗的临床疗效和通畅率。方法从2009年10月到2011年7月,32例(39条下肢)下肢ASO患者在上海交通大学附属第六人民医院行介入治疗。回顾性分析32例ASO患者的血管造影图像,根据病变长度和程度分级。对手术成功患者随访,随访期3～16个月,平均随访期(8.7±1.9)个月。随访期内每3个月进行一次下肢MRA或CTA检查,并搜集相关临床资料。结果技术成功率93%,踝肱指数(ankle-brachial index,ABI)从术前的0.47±0.11提高至术后的0.68±0.02,在随访期末20例取得了稳定疗效,总的通畅率为77%,保肢率为97%。结论介入治疗ASO安全可行,取得了良好的临床效果及通畅率,其长期疗效尚需进一步观察。
Objective To retrospectively analyze the clinical efficacy and patency of arteriosclerosis obliterans (ASO) interventional therapy. Methods From October 2009 to July 2011, 32 ASO (lower extremities) ASO patients were involved in the intervention in the Sixth People’s Hospital Affiliated to Shanghai Jiaotong University. The angiographic images of 32 patients with ASO were retrospectively analyzed and graded according to the length and extent of the lesion. The patients were followed up for 3 to 16 months with an average follow-up of 8.7 ± 1.9 months. Follow-up period every 3 months for a lower limb MRA or CTA examination, and collect relevant clinical data. Results The technical success rate was 93%. The ankle-brachial index (ABI) increased from 0.47 ± 0.11 before operation to 0.68 ± 0.02 after operation. A stable response was achieved at the end of the follow-up period with a total patency rate of 77 %, Limb salvage rate of 97%. Conclusion Interventional treatment of ASO is safe and feasible, and has achieved good clinical effect and patency rate, its long-term efficacy needs further observation.