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应用特定的标准选择前瞻性试验汇总进行 Meta分析 ,通过对照以皮质类固醇、安慰剂治疗和不治疗完全性特发性面瘫 (IFNP)病人的结果 ,评价其面神经功能的恢复。临床上的完全性、不完全性的面神经运动功能的恢复作为终点测量值。通过计算率差和 Fisher精确检验的 P值来评价效果的分级和意义。用随机效果模型进行综合分析。数据分析显示皮质类固醇疗法能提高 17%的完全性 IFNP病人的面神经运动功能恢复率。皮质类固醇治疗对完全性 IFNP的功能恢复有临床上和统计学上的意义
Meta-analysis was performed using a prospective trial-specific selection of prospective trials to assess the recovery of facial nerve function by comparing the results of patients treated with corticosteroids, placebo, and no treatment of patients with complete idiopathic facial paralysis (IFNP). Clinically complete, incomplete recovery of facial motor function was used as the endpoint measure. By calculating the rate difference and Fisher’s exact test of the P value to evaluate the effect of classification and significance. Use random effects model for comprehensive analysis. Data analysis showed that corticosteroid therapy increased facial motor recovery in 17% of patients with complete IFNP. Corticosteroid therapy has clinical and statistical significance for the functional recovery of complete IFNP