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1985年,Rosenberg报告用淋巴因子活化的淋巴细胞(LAK)治疗肿瘤患者并取得疗效。1991年我国姚氏等报道自外周静脉回输LAK细胞治疗乙型肝炎,效果令人鼓舞。但肝内注射LAK细胞治疗乙型肝炎尚未见到报道。本文采用在B超引导下,经皮肝穿肝内注射体外活化的自体淋巴细胞治疗6例乙型慢活肝和3例乙型肝炎后肝硬化,近期疗效尚称满意,现将治疗结果报道如下。临床资料一、病例选择:本组均为男性,年龄25～41岁(平均31.3岁),依据入院顺序将12例乙型慢活肝和6例乙型肝炎后肝硬化,随机分为肝内注射组和对照组(未给予抗病毒治疗)。全部病例符合1990年第六次全国病毒性肝炎会
In 1985, Rosenberg reported treatment of tumor patients with lymphokine-activated lymphocytes (LAK) and achieved efficacy. In 1991, Yao et al reported that treatment of hepatitis B with LAK cells from peripheral venous return was encouraging. However, intrahepatic injection of LAK cells for the treatment of hepatitis B has not been reported. In this paper, under the guidance of B-ultrasound, percutaneous transhepatic injection of activated autologous lymphocytes in vitro treatment of 6 cases of slow-B slow liver and 3 cases of hepatitis B cirrhosis, the short term efficacy is still satisfied with the results reported as follows. Clinical data A case selection: This group are male, aged 25 to 41 years (mean 31.3 years), according to the order of admission 12 cases of slow living hepatitis B and 6 cases of hepatitis B cirrhosis, were randomly divided into intrahepatic Injection group and control group (no antiviral treatment). All cases are in line with the sixth national infectious hepatitis in 1990