本研究应用原子吸收分光光度法，检测１８６例肺癌病人血清铜、锌水平，并以１６０例正常人和６４例良性胸部疾患病人作对照。结果显示：肺癌病人血清铜水平明显高于良性胸部疾患病人和正常人。血清锌水平明显低于良性胸部疾患病人和正常人。铜、锌水平的改变与肺癌的病期有明显的关系（Ｐ＜０．０１），而与组织学类型无关。本研究结果表明：检测肺癌病人血清铜、锌水平可用于肺癌的辅助诊断和判别肺癌的病期。 In this study, atomic absorption spectrophotometry was used to detect serum copper and zinc levels in 186 patients with lung cancer, and 160 healthy subjects and 64 patients with benign chest diseases were used as controls. The results showed that serum copper levels in patients with lung cancer were significantly higher than those in benign breast disease patients and normal people. Serum zinc levels were significantly lower than in patients with benign chest diseases and normal persons. The changes of copper and zinc levels were significantly related to the stage of lung cancer (P<0.01), but not to the histological type. The results of this study indicate that the detection of serum copper and zinc levels in lung cancer patients can be used for the auxiliary diagnosis of lung cancer and to distinguish the stage of lung cancer.