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神经鞘脂(sphingolipid)分为鞘磷脂和鞘糖脂两大类,它不仅是真核细胞生物膜的组成成分,同时在不同的物种中都发挥了广泛的生理作用。以往的研究多关注于鞘磷脂和鞘糖脂在细胞粘附、细胞膜的形成、信号转导、神经元的髓鞘形成和细菌毒素的结合中发挥的作用,而其代谢产物神经酰胺(ceramide)、鞘氨醇(sphingosine)和1-磷酸鞘氨醇(spingosine-1-phosphate)的作用并未引起重视。随
Sphingolipid is divided into sphingolipids and sphingolipids two categories, it is not only the composition of eukaryotic biofilm, while in different species have played a wide range of physiological effects. Previous studies have mostly focused on the roles of sphingomyelin and sphingoglycolipids in cell adhesion, cell membrane formation, signal transduction, myelination of neurons and the binding of bacterial toxins, and their metabolites ceramide, , Sphingosine and spingosine-1-phosphate did not attract much attention. With