We demonstrate a new scheme for generation of optical frequency comb (OFC) based on cascade modulators, 23 comb lines within 0.5 dB spectral power variation are obtained. An optical finite impulse response (FIR) filter is introduced for suppression of amplified spontaneous emission noise. It is shown that carrier-to-noise-ratio of the OFC generated by this scheme can be as high as 38.8 dB with 12 dB improvement by using a 16-tap FIR filter, and the error vector magnitude performances of loaded Nyquist-16 quadrature amplitude -modulation signal is improved from 14.20% to 7.44%.