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目的:评价自拟凉血清肺汤联合西医常规疗法治疗玫瑰痤疮肺胃热盛证临床疗效。方法:将符合入选标准的2017年5月-2019年5月本院玫瑰痤疮患者312例采用随机数字表法分为2组，每组156例。对照组口服盐酸多西环素片并配合外敷甲硝唑凝胶治疗，研究组在对照组基础上加服自拟凉血清肺汤。2组均治疗4周。采用皮肤病生活质量指数(Dermatology Life Quality Index, DLQI)评价患者的生活质量，采用多功能皮肤测试仪测量皮损区红斑指数(erythema index, EI)，记录治疗期间的不良反应，评价临床疗效。结果:研究组总有效率为80.8%(126/156)、对照组为66.7%(104/156)，2组比较差异有统计学意义(n χ2＝8.012，n P＝0.005)。治疗后，研究组生理、心理、家庭、社会活动、人际交往和职业限制、治疗评分均低于对照组(n t值分别为17.942、15.794、19.465、21.586、31.375、27.472，n P值均<0.001)；EI[(619.69±71.53)比(822.97±89.47)，n t＝32.348]低于对照组(n P<0.01)。治疗期间，对照组不良反应发生率为4.5%(7/156)、研究组为5.8%(9/156)，2组比较差异无统计学意义(n χ2＝0.439，n P＝0.514)。n 结论:自拟凉血清肺汤联合西医常规疗法可有效改善玫瑰痤疮肺胃热盛证患者的临床症状及生活质量，提高临床疗效且安全性较好。“,”Objective:To evaluate the clinical efficacy of self-made n Liangxue-Qingfei Decoction combined with conventional western medicine in the treatment of rosacea with excessive heat in lung and stomach.n Methods:312 patients with rosacea in Longfu hospital from May 2017 to May 2019 were selected and randomly divided into two groups, 156 cases in each group. The control group was treated with Doxycyclane Hyclate Tablets combined with Metronidazole Gel The study group was additionally given self-made n Liangxue-Qingfei Decoction on the basis of the control group. Both groups were treated for 4 weeks. Dermatology Life Quality Index (DLQI) was evaluated . The erythema index (EI) of lesion area was measured by multi-functional skin tester. The adverse reactions during the treatment were recorded and the clinical efficacy was evaluated.n Results:The total effective rate was 80.8% (126/156) in the study group and 66.7% (104/156) in the control group, with statistically significance (n χ2=8.012, n P=0.005). After the treatment, the scores of physiology, psychology, family, social activities, interpersonal and occupational restrictionsin, and treatment in the study group were lower than those in the control group (n t=17.942, 15.794, 19.465, 21.586, 31.375, 27.472, n P<0.001); EI (619.69 ± 71.53n vs. 822.97 ± 89.47, n t=32.348) was lower than that of the control group (n P<0.01). During the treatment, the incidence of adverse reactions was 4.5% (7/156) in the control group and 5.8% (9/156) in the study group, and there was no significant difference between the two groups (n χ2=0.439, n P=0.514).n Conclusion:The self-made n Liangxue-Qingfei Decoction combined with routine western medicine therapy can effectively improve the clinical symptoms and quality of life of rosacea patients with lung and stomach excessive heat, improve the clinical efficacy with safety.n