人参中所含的主要活性成分——人参皂苷具有广泛的药理作用,如抗肿瘤、抗炎等。近来研究者围绕人参皂苷进行的研究,主要是从分子水平上来阐明其作用机制,其中JNK信号通路逐渐得到了重视,人参皂苷的许多药理活性均与JNK密切相关。我们就人参皂苷对JNK调控作一综述。 Ginseng contains the main active ingredient - ginsenosides has a wide range of pharmacological effects, such as anti-tumor, anti-inflammatory and so on. Recently researchers around ginsenosides research, mainly from the molecular level to elucidate its mechanism of action, JNK signaling pathway has gradually been taken seriously, many of the pharmacological activities of ginsenosides are closely related with JNK. We reviewed the regulation of JNK on ginsenosides.