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1一般资料患者男,57岁,农民,出生并长期居住于内蒙古。左足跟起皮疹伴疼痛3年。3年前,患者的左足跟外侧缘皮肤外伤后出现针尖大红色丘疹,伴针刺样疼痛,后逐渐增大并隆起,患者自行挑破皮损后持久不愈,且疼痛加剧。外院予双氧水冲洗和外用阿达帕林、咪喹莫特及夫西地酸乳膏治疗,无效。1年前在外院行该皮损部分切除术,术中切除物组织病理检查示:表皮明显角化过度,颗粒层肥厚,表皮增生呈锯齿状,基底层液化,真皮
1 General Information Patient Male, 57 years old, farmer, born and long-term resident in Inner Mongolia. Left heel rashes with pain for 3 years. Three years ago, the patient’s left heel and lateral margin of the skin after injury appeared needle tip red papules, with acupuncture-like pain, and then gradually increased and uplift, the patient self-scratching skin lesions lasting unhealed, and the pain worsened. External hospital to hydrogen peroxide flushing and topical adapalene, imiquimod and fusidic acid cream treatment, invalid. A year ago in the outer hospital line partial excision of the lesion, intraoperative resectable tissue histopathology showed: epidermal hyperkeratosis, granulomatous hypertrophy, epidermal hyperplasia jagged, basal layer liquefaction, leather