氮杂环状化合物是一类重要的有机分子并在自然界中广泛存在,很多这类化合物具有生理活性,是农药、医药、染料和功能分子材料的核心骨架.本工作通过钯催化三炔经历分子内的[4+2]环化加成反应,发展了一种高效实用地制备炔官能化苯并二氢异吲哚衍生物的Domino方法.所合成目标产物的结构经各种波谱手段表征确证,其中化合物2g的结构还通过X射线单晶衍射分析确认. Nitrogen heterocyclic compounds are a kind of important organic molecules and widely exist in nature. Many of these compounds have physiological activities and are the core skeletons of pesticides, pharmaceuticals, dyes and functional molecular materials.In this work, And the [4 + 2] cycloaddition reaction, an efficient and practical method for the preparation of alkyne-functionalized benzodihydroisoindole derivatives Domino method was developed by the structure of the target product was characterized by a variety of spectroscopic methods to confirm , Where the structure of compound 2g was also confirmed by X-ray single crystal diffraction analysis.