胃癌高发区高危人群普查检出胃癌的特点分析

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目的探讨胃癌高发区高危人群普查检出的胃癌的特点。方法采用两轮筛选法,第一轮选择35岁以上并有胃病史或胃癌家族史者 ,检测血清胃蛋白酶含量并进行胃双重对比检查,第二轮进行胃镜检查及病理活检。结果3033例进行第一轮检查后,筛选出1781例进行第二轮的胃镜检查及病理活检,发现胃癌32例,其中早期胃癌18例,占56.25 %,进展期胃癌14例,占43.75 %;早期胃癌中混合型较多 (9例 ),并且发现5例一点癌;进展期胃癌中 ,溃疡浸润型胃癌(BorrmannⅢ型 )13例;组织学分型中多为管状腺癌 (25例 )。结论胃癌高发区高危人群中胃癌检出率较高,而且早期胃癌较多,对此人群有针对性地、有计划地开展一、二级预防具有重要意义 Objective To investigate the characteristics of gastric cancer detected by general survey of high-risk population in high-risk areas of gastric cancer. METHODS: Two rounds of screening were used. The first round selected 35-year-old patients with a history of stomach or family history of gastric cancer. Serum pepsin levels were measured and double-contrast examinations were performed. The second round of gastroscopy and biopsy were performed. Results After the first round of examination in 3033 cases, 1781 cases were screened for the second round of gastroscopy and biopsy. 32 cases of gastric cancer were found, including 18 cases of early gastric cancer, accounting for 56.25%, and 14 cases of advanced gastric cancer, accounting for 43.75%; There were more mixed types of early gastric cancer (9 cases), and 5 cases of a little cancer were found. In advanced gastric cancer, 13 cases of ulcer-infiltrating type of gastric cancer (Borrmann type III) were involved. In histologic type, there were mostly tubular adenocarcinomas (25 cases). Conclusion The detection rate of gastric cancer in high-risk populations with high incidence of gastric cancer is high, and there are more early gastric cancers. It is of great significance for the population to carry out targeted primary and secondary prevention in a targeted and planned manner.
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