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20世纪70年代以前,肠球菌被认为是一种容易实施抗菌药物治疗且相对无害的病原体,但是近年来肠球菌已逐渐成为院内感染的重要病原菌,且临床分离的肠球菌对抗菌药物的耐药性也在逐年增加,尤其是耐万古霉素肠球菌(vancomycin resistant enterococcus,VRE)的出现,使临床上抗菌药物的选择面临着巨大挑战。为此,将VRE的流行病学作一综述,以期对有效预防及控制其感染提供科学依据。
Enterococci were considered to be a relatively innocuous pathogen for antimicrobial therapy before the 1970s, but enterococci have gradually become an important pathogen of nosocomial infections in recent years, and clinically isolated enterococci are resistant to antimicrobials The emergence of vancomycin resistant enterococcus (VRE) is also increasing year by year, making the choice of clinical antimicrobial drugs a huge challenge. Therefore, the epidemiology of VRE is reviewed in order to provide a scientific basis for effective prevention and control of the infection.