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乳腺印戒细胞型导管原位癌(signet ring cell ductal carcinoma in situ of the breast)因具有独特的细胞学形态(印戒形态、产生胞质内黏液),被列为一种独立的导管原位癌(ductal carcinoma in situ,DCIS)类型。在十几种DCIS中相对少见,其分化较差,级别较高,侵袭性强,预后不良,其诊断应与其他表现为印戒细胞形态的乳腺原发或继发肿瘤相鉴别。现报道1例,并结合相关文献复习,对其临床病理学特点、免疫表型等进行探讨。
Signet ring cell ductal carcinoma in situ of the breast is classified as a separate ductal origin due to its unique cytological morphology (signet ring morphology, producing intracytoplasmic mucus) The type of ductal carcinoma in situ (DCIS). In more than a dozen DCIS relatively rare, poorly differentiated, high grade, aggressive, poor prognosis, the diagnosis should be with other signs of primary or secondary signet ring cell morphology differentiated breast cancer. We report 1 case, combined with relevant literature review, its clinical and pathological features, such as immunophenotype to explore.