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有关门静脉高压最主要、最危险的并发症——食管静脉曲张出血的治疗,由于下列三方面重要而又互有联系的发展,已发生了显著的变化。 1.门静脉高压是伴有自主神经系统活动显著改变的全身性疾病,心输出量增加、外周阻力降低的高动力学状态是其突出的血流动力学变化。 2.业已发现各种体液因素在门静脉高压的发病机制中起着重要的作用,这就提示在门静脉高压中存在某种可逆的因素,从而开辟了
The treatment of esophageal variceal bleeding, the chief and most dangerous complication of portal hypertension, has changed dramatically since the following three important but interconnected developments. 1. Portal hypertension is a systemic disease with significant changes in autonomic nervous system activity. High kinetic states with increased cardiac output and decreased peripheral resistance are prominent hemodynamic changes. 2. It has been found that various body fluid factors play an important role in the pathogenesis of portal hypertension, suggesting that there is some reversible factor in portal hypertension that opens up