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目的 :对大肠良恶性肿瘤患者 32 8例作血清癌胚抗原 (CEA)水平测定 ,其中进展期大肠癌 (A组 ) 16 3例 ,早期大肠癌 (B组 ) 18例 ,肿瘤性息肉 (C组 ) 99例 ,非肿瘤性息肉 (D组 ) 4 8例 ,旨在探讨 CEA水平对四组疾病的诊断价值和临床意义。方法 :采用单克隆抗体测定 ,血清 CEA≥ 5 μg/ L 为阳性 ,各组间比较用统计学检验。结果 :CEA阳性计数和 CEA值计量均为 A>B>C>D组 (P <0 .0 1或 <0 .0 5 )。结论 :血清 CEA检测用于进展期大肠癌的诊断及预后判断有临床价值 ,用于早期大肠癌的诊断尚缺乏价值 ,并提示肿瘤性息肉具有恶性潜能
Objective: To determine the level of serum carcinoembryonic antigen (CEA) in 32 patients with benign and malignant colorectal cancer, including 16 3 cases of advanced colorectal cancer (A group), 18 cases of early colorectal cancer (Group B), and 18 cases of tumorous polyp Group) 99 cases, non-tumor polyps (group D) 48 cases, to investigate the diagnostic value of CEA levels and the four groups of diseases and clinical significance. Methods: Monoclonal antibody was used to determine the serum CEA ≥ 5 μg / L as positive. Statistical comparison was made between groups. Results: The CEA positive counts and CEA values were all A> B> C> D (P <0.01 or <0.05). Conclusion: Serum CEA test has clinical value in the diagnosis and prognosis of advanced colorectal cancer. It is still lack of value in the diagnosis of early stage colorectal cancer and suggests that malignant potential of tumor polyp