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[目的]观察健脾化瘀汤联合西药治疗胃癌疗效。[方法]使用随机平行对照方法,将70例住院患者按抽签法随机分为两组。对照组35例FLE化疗方案,前1~5d,100g甲酰四氢叶酸钙(CF)和依托泊甙(VP-16),1次/d,静滴;后750mg氟尿嘧啶(5-Fu),1次/d,静滴。治疗组35健脾化瘀汤(茯苓、党参各30g,甘草、半夏、土鳖、乌蛇、厚朴各10g,蜈蚣2条,白术15g;胃脘疼痛加九香虫、白芍、索罗子各30g;神疲乏力加西洋参10g,黄芪30g;食欲不振加炒三仙30g);1剂/d,水煎200m L早晚温服;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、生活质量、体力状况、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效23例,有效9例,无效3例,总有效率91.42%。对照组显效11例,有效17例,无效7例,总有效率80.00%。治疗组疗效优于对照组(P<0.05)。两组生活质量、体力状况均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]健脾化瘀汤联合西药治疗胃癌效果显著,值得推广。
[Objective] To observe the therapeutic effect of Jianpi Huayu Decoction combined with western medicine on gastric cancer. [Methods] Randomized parallel method was used to divide 70 hospitalized patients into two groups according to the random selection method. Control group, 35 cases of FLE chemotherapy, 1 ~ 5d before, 100g calcium leucovorin (CF) and etoposide (VP-16), 1 times / d, intravenous drip; after 750mg fluorouracil (5-Fu) 1 times / d, intravenous infusion. The treatment group 35 Jianpi Huayu Decoction (Poria, Codonopsis 30g, licorice, Pinellia, Eupolyphaga, black snake, Magnolia 10g, centipede 2, Atractylodes 15g; stomach ache pain plus nine insects, white peony root, Sorrow Sub-30g; Shenpi fatigue plus American ginseng 10g, Astragalus 30g; loss of appetite plus fried Sanxian 30g); 1 / d, decoction 200m L morning and evening warm clothes; Western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observed clinical symptoms, quality of life, physical condition, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Result] In the treatment group, 23 cases were markedly effective, 9 cases were effective, 3 cases were ineffective, and the total effective rate was 91.42%. In the control group, 11 cases were markedly effective, 17 cases were effective, 7 cases were ineffective, and the total effective rate was 80.00%. The treatment group was better than the control group (P <0.05). The quality of life and physical condition of both groups improved (P <0.05), and the treatment group improved better than the control group (P <0.05). [Conclusion] Jianpi Huayu Decoction combined with western medicine has significant effect on gastric cancer and is worth popularizing.