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动脉粥样栓塞性脑梗塞(ABI)是老年人常见疾病,其危险因素包括男性、既往ABI史、短暂性脑缺血发作、高血压、糖尿病和吸烟等。作者研究了老年ABI患者随访期间的新ABI发生率,旨在探讨其与上述危险因素的关系。对象与方法研究对象为2152例老年人。其中男性664例,平均年龄80±8岁,平均随访42例±5个月;女性1488例,平均年龄82±8岁,平均随访48±30个月。空腹采静脉血测定血清总胆固醇、高密度脂蛋白胆固醇(HDL-C)和甘油三酯(TG)浓度。结果男性发生新ABI者占21%,女性占17%,后者明显少于前音(P=0.043)。男性发生新的ABI事件者中,有、无既往ABI史者分别占39%、
Atherothrombotic cerebral infarction (ABI) is a common disease in the elderly, and its risk factors include males, previous history of ABI, transient ischemic attack, hypertension, diabetes and smoking. The authors studied the incidence of new ABI during follow-up in elderly patients with ABI to explore its association with these risk factors. Subjects and Methods The object of study was 2152 elderly people. There were 664 males, mean age 80 ± 8 years, with an average follow-up of 42 months ± 5 months; females 1488 cases, with an average age of 82 ± 8 years, with an average follow-up of 48 ± 30 months. Serum total cholesterol, high density lipoprotein cholesterol (HDL-C) and triglyceride (TG) concentrations were determined by fasting venous blood. Results The incidence of new ABI in males was 21% and in females 17%, which was significantly less than that of anterior tone (P = 0.043). Among the new ABI events in men, there were 39% of those with no prior history of ABI,