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目的:探讨八正汤剂联合盐酸坦索罗辛缓释胶囊治疗慢性非细菌性前列腺炎临床疗效观察及安全性评价。方法:选择2012年8月—2013年8月期间在本院接受诊治的慢性非细菌性前列腺炎患者96例。按照随机数字表法将96例患者随机分为对照组(48例)与治疗组(48例)。对照组给予盐酸坦索罗辛缓释胶囊;治疗组在对照组基础上给予八正汤剂。两组患者一般资料之间对比分析差异无统计学意义(P>0.05)。结果:治疗组治疗后总有效率(91.67%)显著高于对照组治疗后总有效率(79.17%),且有显著性差异(P<0.05);治疗组治疗后NIH-CPSI评分(11.92±6.85)显著低于对照组(17.14±7.32),且有显著性差异(P<0.05)。结论:八正汤剂联合盐酸坦索罗辛缓释胶囊治疗慢性非细菌性前列腺炎临床疗效显著,具有重要临床价值。
Objective: To investigate the clinical efficacy and safety of “Bazheng Decoction” combined with tamsulosin hydrochloride sustained-release capsules in the treatment of chronic nonbacterial prostatitis. Methods: A total of 96 patients with chronic nonbacterial prostatitis admitted to our hospital from August 2012 to August 2013 were selected. According to the random number table method, 96 patients were randomly divided into control group (48 cases) and treatment group (48 cases). The control group was given tamsulosin hydrochloride sustained release capsules; the treatment group was given Bazheng decoction on the basis of the control group. There was no significant difference between the two groups in general data (P> 0.05). Results: The total effective rate (91.67%) in the treatment group was significantly higher than that in the control group (79.17%) after treatment, and there was a significant difference (P <0.05). The NIH-CPSI score (11.92 ± 6.85) was significantly lower than the control group (17.14 ± 7.32), and there was a significant difference (P <0.05). Conclusion: Bazheng decoction combined with tamsulosin hydrochloride sustained-release capsules in the treatment of chronic non-bacterial prostatitis has significant clinical effect and has important clinical value.