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目的：探讨准分子激光屈光性角膜切削术后治疗疼痛的最佳处理方法。方法：２４０ 例近视术后患者分为４ 组，Ⅰ组０ ．１ ％ 双氯酚酸钠点眼，Ⅱ组１ ％ 潇莱威点眼，Ⅲ组双氯酚酸钠＋ 潇莱威点眼，以上３ 组必要时均口服散利痛片和安定片；Ⅳ组双氯酚酸钠＋ 潇莱威点眼，口服长效曲马多片和安定片。分别观察患者术后疼痛自主评分、手术当晚睡眠时间、服用镇痛药剂量及角膜上皮愈合时间。结果Ⅰ、Ⅱ、Ⅲ组用药后疼痛仍较明显，自主评分为５ ．９ ±０ ．７２ ，６ ．３ ±０ ．６９ ，５ ．５ ±０ ．７１ ；睡眠时间３ ．９ ±０ ．２３ ，３ ．６ ±０ ．２７ ，３ ．８ ±０ ．３１ 小时；服散利痛１ ．８５ ±０ ．７１ ， １ ．９５ ±０ ．９３ ，１ ．６５ ±０ ．６６克。Ⅳ组仅为隐痛，评分２ ．７ ±０ ．４３ ，睡眠时间６ ．７ ±０ ．２０ 小时，与前３ 组相比有显著差异（ Ｐ ＜ ０ ．０５） ，各组角膜上皮愈合时间无显著差异。结论：Ⅳ组联合用药为最佳处理方式，可供临床选用。
Objective: To investigate the best treatment for pain after excimer laser refractive keratectomy. Methods: 240 cases of myopia patients were divided into 4 groups, Ⅰ group 0. 1% Diclofenac spot, Ⅱ 1% Xiaoweiwei point eyes, Ⅲ group diclofenac sodium and Xiaoweiwei point of eye, the above three groups were required oral oral sore throat and diazepam tablets; Ⅳ group of two chlorine Sodium phenothiazole + Xiaoweiwei point of eye, oral long-acting tramadol tablets and stability tablets. Patients were observed after the pain score, sleep night surgery, taking analgesic dose and corneal epithelial healing time. Results The pain in group Ⅰ, Ⅱ and Ⅲ was still more obvious with self - rated score 5. 9 ± 0. 72, 6. 3 ± 0. 69, 5. 5 ± 0. 71; sleep time 3. 9 ± 0. 23, 3. 6 ± 0. 27, 3. 8 ± 0. 31 hours; clothes soreong 1. 85 ± 0. 71, 1. 95 ± 0. 93, 1. 65 ± 0. 66 grams. Ⅳ group only for pain, score 2. 7 ± 0. 43, sleep time 6. 7 ± 0. 20 hours, compared with the previous three groups were significantly different (P <0 .05), corneal epithelial healing time was no significant difference. Conclusion: The combination of Ⅳ group is the best treatment for clinical use.