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过期流产是一种常见的病理妊娠现象,其原因复杂,相关报道大多关注染色体、感染、内分泌、抗生殖免疫抗体等因素~([1-2]),然而过期流产的机制尚未阐述明确,随着分子生物学技术的发展,利用基因组学和蛋白质组学方面的知识建立一种可靠、精确的检测机制,进行分子诊断来探讨过期流产的机制,完成产前诊断,有相对的准确率、特异性以及预期性。本文就影响胚胎绒毛组织发育导致过期流产的相关基因或细胞因子的研究进展阐述如下。
Abortion is a common pathological pregnancy pregnancy, the reasons are complex, the relevant reports are mostly concerned about chromosomes, infections, endocrine, anti-immune antibody and other factors ~ ([1-2]), but the mechanism of overdue abortion has not been clearly defined, with The development of molecular biology techniques, the use of genomics and proteomics knowledge to establish a reliable and accurate detection mechanism for molecular diagnosis to explore the mechanism of overdue abortion to complete prenatal diagnosis, a relative accuracy, specificity Sexuality and anticipation. This article on the impact of embryonic villi tissue development led to outdated abortion-related genes or cytokines are described below.