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目的:评价痰热清注射液与头孢呋辛酯片对高血压脑出血患者术后抗感染的临床疗效及其对炎症因子的影响。方法:选取2015年6月—2016年6月间收治的高血压脑出血患者80例,采用随机分组法将其分为观察组和对照组,每组40例;对照组患者给予头孢呋辛酯片常规对症治疗,观察组患者在对照组治疗基础上加用痰热清注射液治疗;评价两组患者治疗后的总有效率以及治疗前后C-反应蛋白(CRP)和IL-1水平变化。结果:观察组患者临床治疗后的总有效率显著高于对照组(P<0.05);两组患者治疗后CRP以及IL-1水平值均有所下降,观察组低于对照组(P<0.05)。结论:采用痰热清注射液与头孢呋辛酯片联用治疗高血压脑出血术后感染患者,抗感染的疗效优于单用头孢呋辛酯片和疗效。
Objective: To evaluate the clinical efficacy of Tanreqing Injection and cefuroxime axetil injection on postoperative anti-infection in patients with hypertensive intracerebral hemorrhage and its effect on inflammatory cytokines. Methods: Eighty patients with hypertensive intracerebral hemorrhage admitted between June 2015 and June 2016 were randomly divided into observation group and control group, 40 cases in each group. Patients in the control group were given cefuroxime axetil The patients in the observation group were treated with Tanreqing Injection on the basis of the control group. The total effective rate and the levels of C-reactive protein (CRP) and IL-1 in the two groups were evaluated before and after treatment. Results: The total effective rate of clinical observation group was significantly higher than that of control group (P <0.05). The CRP and IL-1 levels of both groups decreased after treatment, and the observation group was lower than the control group (P <0.05) ). Conclusion: Tanreqing injection and cefuroxime axetil tablets combined treatment of patients with hypertensive intracerebral hemorrhage postoperative infection, the anti-infective efficacy is better than single Cefuroxime axetil tablets and curative effect.