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目的 评价乙型肝炎疫苗免疫实施方案和远期效果。方法 考核乙肝疫苗接种率、及时率、孕妇HBV筛检率和阳性率,并对1986年出生时接种乙肝疫苗的对象随访采血,检测HBsAg、抗-肿s、抗-HBc。并设免前本区及邻区乙肝疫苗未免疫者为内、外对照。结果 免后14年HBsAg阳性率在1％以下,与内、外对照相比下降幅度达90％,远期保护效果为81.23％。结论 免后14年仍无需加免。
Objective To evaluate the implementation of hepatitis B vaccine and its long-term efficacy. Methods Hepatitis B vaccination rate, timely rate, HBV screening rate and positive rate in pregnant women were evaluated. Blood samples were collected from HBsAg-infected subjects at birth in 1986 to detect HBsAg, anti-swollen s and anti-HBc. And set before the district and neighboring areas unhealthy hepatitis B vaccine for internal and external controls. Results After 14 years, the positive rate of HBsAg was less than 1%, and the decline rate was 90% compared with the internal and external controls. The long-term protective effect was 81.23%. Conclusion 14 years after the exemption still need to add free.