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目的 :提出基于高阶过零 (HOC)的方法并利用EEG检测由于缺氧窒息而引起的中枢神经系统损伤及对损伤程度进行定量评估。方法 :采用两种基于HOC的方法 ,一种为依据EEG信号序列统计分布特性的HOCSD(S距离 )法 ,另一种为依据预处理后EEG信号的谱特性的HOCCF法。结果 :对三类实验样本进行了检测 ,检测结果与神经缺欠值 (NDS)的相关性高达 96 %。结论 :实验数据分析表明 ,两种基于HOC的新方法对于检测由于缺氧窒息而引起的中枢神经系统损伤及对损伤程度进行定量评估具有一定的意义。
OBJECTIVE: To propose a method based on high-order zero-crossing (HOC) and use EEG to detect central nervous system injury caused by hypoxia and asphyxia and to quantitatively evaluate the degree of injury. Methods: Two HOC-based methods were used, one was the HOCSD (S-distance) method based on the statistical distribution of EEG signal sequences and the other was the HOCCF method based on the spectral characteristics of the pre-processed EEG signals. Results: Three types of experimental samples were tested. The correlation between the results and NDS was as high as 96%. CONCLUSION: The experimental data analysis shows that two new HOC-based methods are of great significance for the detection of central nervous system injury and quantitative assessment of injury due to hypoxia and asphyxia.