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众所周知,结肠菌丛在炎性肠病(IBD)的发生上起重要作用。肠道黏膜免疫系统被某些共生菌无限制地激活可能是炎性肠病持续不愈和反复发作的原因。大多数实验和临床研究提示,微生态制剂(包括益生菌和益生元)对IBD,特别是治疗和减少囊袋炎和溃疡性结肠炎复发有较明显作用,其对克罗恩病的治疗作用尚有一定争论。微生态制剂应用的目的在于刺激宿主的免疫系统,调节局部免疫功能以修复受损的黏膜病变。
It is well-known that colon flora plays an important role in the development of inflammatory bowel disease (IBD). Intestinal mucosal immune system by some symbionts unlimited activation may be the cause of inflammatory bowel disease continued uninterrupted and recurrent. Most experimental and clinical studies suggest that probiotics, including probiotics and prebiotics, have a more pronounced effect on IBD, especially in the treatment and reduction of recurrence of vesiculitis and ulcerative colitis, and its therapeutic effect on Crohn’s disease There is still some debate. The purpose of probiotics is to stimulate the host’s immune system and to regulate local immune function to repair damaged mucosal lesions.