结节性多动脉炎(PolyarteritisNodosa,PN)是一种原因不清的,少见的结缔组织疾病,迄今国内只见少量临床、尸检报告及临床病理讨论此病常累及肾脏而引起肾多动脉炎和坏死性肾小球肾炎.但是,引起肾小管功能损害者罕见,国内也未见报告.本文报道一例PN并肾小管性酸中毒(RTA)患者,并结合文献复习以供同道参考. Polyarteritis Nodosa (PN) is an unclear and uncommon connective tissue disease. So far, only a few clinical and autopsy reports have been reported in China and clinicopathological studies. The disease often involves the kidneys and causes renal polyarteritis and Necrotic glomerulonephritis, but caused by renal tubular dysfunction are rare, no domestic report.We report a case of PN and renal tubular acidosis (RTA) patients, combined with the literature review for fellow reference.