HER2基因及其表达的蛋白质在许多恶性肿瘤的发生、发展过程中起重要作用,是判断癌症预后和指导治疗的重要指标。在乳腺癌和胃癌中,针对HER2蛋白的靶向治疗药物曲妥珠单抗(trastuzumab,商品名为赫赛汀Herceptin)已广泛应用于临床并取得了显著疗效,给其他癌症的治疗带来希望,尤其是对预后极差、几乎无有效干预措施的胰腺 HER2 gene and its expressed protein plays an important role in the occurrence and development of many malignant tumors and is an important index for judging cancer prognosis and guiding treatment. In breast and stomach cancer, the trastuzumab (HERCEPTIN® Herceptin), a targeted therapy for HER2 protein, has been widely used clinically and has achieved significant results, prompting hopes for the treatment of other cancers , Especially for the pancreas, which has a poor prognosis and few effective interventions