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本文采用酶联免疫吸附试验(ELISA)一双抗体夹心法和竞争性蛋白结合法,检测了急性乙型肝炎急性期病人和正常人血清总EgE水平与血浆中cAMP含量.结果表明病,人的血清总IgE水平明显高于正常人,而血浆中cAMP含量却显著低于正常对照组.提示,IgE及其介导的Ⅰ型变态反应可能参与急性乙型肝炎的发病过程.
In this study, ELISA and a sandwich enzyme-linked immunosorbent assay (ELISA) were used to detect serum total EgE levels and plasma cAMP levels in acute and chronic hepatitis B patients. The results showed that the disease, human serum The level of total IgE was significantly higher than that of normal people, while the plasma cAMP content was significantly lower than that of the normal control group, suggesting that IgE and its type I allergic reactions may be involved in the pathogenesis of acute hepatitis B.