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A Compton camera prototype has been devel-oped using a pixelated CZT detector with 4-by-4 pixels. Signals of the detector are read out by a VASTAT ASIC that is controlled by a self-developed DAQ board. The DAQ software is developed using LabVIEW, and the off-line Compton imaging codes are written in C++. The prototype has been successfully calibrated, and its capa-bilities for source detection, spectroscopy, and Compton imaging have been demonstrated using a Cs-137 source. The angular resolution of the 662 keV line is 36° FWHM for the simple back-projection method and 9.6° FWHM for the MLEM reconstruction method. The system is ready to be extended to 11-by-11 pixels in the future, and a better imaging quality can be expected due to the better relative position resolution.