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目的:探讨抗生素不同使用时机对剖宫产术后感染发生情况的影响。方法:选择2010年5月～2011年5月接受剖宫产手术的产妇300例,随机分为A、B、C三组,每组100例。A组术前2 h静脉滴入头孢替安2.0 g;B组术前0.5 h静脉滴入同等剂量的头孢替安;C组术后给予头孢替安静脉滴入2～4天。结果:A组、B组术后体温情况、切口愈合情况、产褥病率和宫腔感染率明显好于C组,住院时间较C组短(P<0.05),B组产妇术后体温及手术切口愈合情况均优于A组(P>0.05),B组产妇的各项感染评价指标均优于A组,但差异无统计学意义(P>0.05)。结论:术前应用抗生素对预防剖宫产术后切口感染有较好的效果,尤其以术前0.5 h给药效果最佳。
Objective: To investigate the different timing of antibiotics on the incidence of post-cesarean section infection. Methods: From May 2010 to May 2011, 300 maternal women undergoing cesarean section were randomly divided into three groups (A, B and C), 100 cases in each group. Group A received cefotiam 2.0 g intravenously 2 hours before operation; Group B received the same dose of cefotenan intravenously 0.5 hours before operation; Group C received cefotiam intravenously 2 to 4 days after operation. Results: The postoperative body temperature, incision healing, puerperal morbidity and intrauterine infection in group A and group B were significantly better than those in group C (P <0.05). The postoperative body temperature and Surgical incision healed better than A group (P> 0.05), B group of maternal infection evaluation index are better than A group, but the difference was not statistically significant (P> 0.05). Conclusion: Preoperative antibiotics have a good effect in preventing incision infection after cesarean section, especially in 0.5 h before surgery.