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目的:了解高铅血症对学龄前儿童神经行为功能发育的影响。方法:采用病例对照研究,对101名4～5岁高铅血症儿童进行Achenbach儿童行为量表评定和视觉选择反应时、视觉注意分配、听觉注意分配、左右手(脚)交叉等神经行为功能测试,并与对照组儿童比较。结果:高铅血症儿童行为问题总分及社会退缩、忧郁、攻击性、多动违纪因子分高于对照组儿童,差异有显著性意义。前者视觉选择反应时、视觉、听觉注意分配正确次数较对照组低,而平均反应时间则延长,两者有显著性差异。结论:低水平的铅暴露即可影响儿童神经行为功能发育。建议各级妇幼保健机构应将集体儿童高铅血症的预防和干预纳入托幼机构儿童保健工作常规。
Objective: To understand the influence of high blood lead on neurobehavioral function in preschool children. Methods: A case-control study was conducted to evaluate the neurobehavioral function of 101 children aged 4 to 5 years with Achenbach assessment of children’s behavior and visual responses during visual acuity assignment, auditory attentional distribution, left-right hand (foot) cross etc. , And compared with control group children. Results: The total scores of behavioral problems of children with hyperlipidemia and social withdrawal, depression, aggressiveness and hyperactivity disorder were higher than those of control children, the difference was significant. The former visual choice reaction, the visual and auditory attention to the correct number of times lower than the control group, while the average response time is extended, both significant differences. Conclusion: Low levels of lead exposure can affect children’s neurobehavioral development. It is recommended that MCH institutions at all levels should incorporate the prevention and intervention of Collective Childhood Hyperaemia into routine child care work in childcare facilities.