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目的观察泮托拉唑联合帕洛诺司琼防治肿瘤患者化疗所致胃肠道反应的疗效。方法选择该院收治的肿瘤化疗患者100例,所有患者均因化疗出现胃肠道反应,通过信封法随机分为试验组和对照组各50例,试验组给予泮托拉唑联合帕洛诺司琼治疗,对照组给予泮托拉唑治疗,对比2组的临床疗效、不良反应及临床症状缓解时间。结果试验组总有效率为98.00%高于对照组的80.00%,不良反应发生率低于对照组,临床症状缓解时间短于对照组,差异均有统计学意义(P<0.05)。结论泮托拉唑联合帕洛诺司琼防治肿瘤患者化疗所致胃肠道反应疗效显著,可减少患者的不良反应,缩短临床症状缓解时间,值得临床推广应用。
Objective To observe the efficacy of pantoprazole and palonosetron in preventing and treating gastrointestinal reactions induced by chemotherapy in cancer patients. Methods 100 cases of tumor chemotherapy patients admitted to the hospital were selected, all patients were gastrointestinal reactions due to chemotherapy, by the envelope method were randomly divided into experimental group and control group of 50 patients, the experimental group was given pantoprazole Palioran Division Joan treatment, the control group was given pantoprazole treatment, the clinical efficacy of the two groups, adverse reactions and clinical symptoms of remission time. Results The total effective rate in the experimental group was 98.00%, which was significantly higher than that in the control group (80.00%). The incidence of adverse reactions was lower than that of the control group. The clinical symptoms were shorter than that of the control group (P <0.05). Conclusions Pantoprazole and palonosetron are effective in preventing and treating gastrointestinal reactions induced by chemotherapy in patients with cancer, which can reduce adverse reactions and shorten the time of clinical symptom relief, which is worthy of clinical application.