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单克隆抗体(Monoclonal Antibody-McAb)1975年由Kohler和Milstein制备成功,80年代初开始用于肿瘤的放射免疫显像(Radioimmunoimaging-RII)及治疗(Radioimmunotherapy-RIT),本文概述该范围近几年的主要进展。 一、试剂: RII与RIT所用试剂为放射性核素标记的McAb,各自的应用情况如下: (一)McAb:用于RII和RIT的McAb,迄今多
The monoclonal antibody (Monoclonal Antibody-McAb) was successfully prepared by Kohler and Milstein in 1975 and was used for radioimmunoimaging-RII and radioimmunotherapy (RIT) in the early 1980s. This article outlines the scope of this study in recent years. The main progress. I. Reagents: The reagents used by RII and RIT are radionuclide-labeled McAbs, and their respective applications are as follows: (a) McAb: McAb for RII and RIT, so far