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目的观察无创正压通气(NIPPV)在治疗慢性阻塞性肺疾病急性加重期(AECOPD)合并呼吸衰竭中的疗效。方法采用回顾性分析的方法,将笔者所在医院2008年1月～2010年1月收治的120例COPD合并Ⅱ型呼吸衰竭患者,在常规治疗的同时,应用无创通气治疗。观察患者通气治疗前、通气治疗2h、24h及通气治疗结束时的动脉血气参数变化,并记录临床好转率。结果 120例患者中,明显好转103例,好转率为85%。与治疗前相比,通气治疗2h、24h及治疗结束时,PaO2明显升高(P<0.05)。结论早期行无创正压通气可以有效治疗COPD合并Ⅱ型呼吸衰竭。
Objective To observe the efficacy of noninvasive positive pressure ventilation (NIPPV) in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) combined with respiratory failure. Methods A retrospective analysis of the method, the author’s hospital from January 2008 to January 2010 admitted 120 cases of COPD patients with type Ⅱ respiratory failure, conventional treatment at the same time, the application of non-invasive ventilation treatment. Ventilation before treatment, ventilation 2h, 24h and ventilation at the end of arterial blood gas parameters change, and record the clinical improvement rate. Results Of the 120 patients, 103 cases improved significantly, the improvement rate was 85%. Compared with before treatment, PaO2 was significantly increased at 2h and 24h after ventilation and at the end of treatment (P <0.05). Conclusion Early noninvasive positive pressure ventilation can effectively treat COPD with type Ⅱ respiratory failure.