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目的采用florisil分散固相萃取-液相色谱串联质谱法对水果中氯吡脲残留的不确定度评定。方法建立该方法的数学模型,对数学模型中各不确定度分量的来源进行分析、量化和合成,得出合成不确定度及其扩展不确定度。结果当水果中氯吡脲含量为10.0μg/kg时,其扩展不确定度为1.4μg/kg(k=2)。结论不确定度主要由标准溶液、标准曲线的建立及测量随机性因素的不确定度引起。该评估模型为液质联用法测定水果中氯吡脲的不确定度评估提供了参考依据。
OBJECTIVE To evaluate the uncertainty of residues of clopidogrel in fruits by florisil dispersive solid-phase extraction-liquid chromatography-tandem mass spectrometry. Methods The mathematical model of this method was established. The sources of all the uncertainty components in the mathematical model were analyzed, quantified and synthesized to obtain the synthetic uncertainty and its extended uncertainty. Results When the content of clopidogrel in fruit was 10.0 μg / kg, its extended uncertainty was 1.4 μg / kg (k = 2). Conclusion The uncertainty is mainly caused by the establishment of standard solution, standard curve and the uncertainty of randomness factor. The evaluation model provides a reference for the evaluation of the uncertainty of the determination of clopidogrel in fruit by liquid chromatography-mass spectrometry.