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目的了解颅内肿瘤患者术后医院感染的临床特点、危险因素及预防治疗措施。方法对2006年1月-2009年12月神经外科收治的306例颅内肿瘤患者术后进行回顾性调查分析。结果 306例颅内肿瘤患者术后发生医院感染22例,感染率7.19%;感染部位以颅内感染为主,占46.15%,其次为切口感染,占23.08%;病原菌以革兰阴性菌为主,铜绿假单胞菌占23.81%。结论颅内肿瘤患者术后医院感染发生率明显高于其他科室,手术时间长、侵入性操作、术中植入物使用、抗菌药物的应用等是医院感染的危险因素。
Objective To understand the clinical features, risk factors and prevention and treatment of nosocomial infections in patients with intracranial tumors. Methods Retrospective analysis was performed on 306 patients with intracranial tumors admitted to Department of Neurosurgery from January 2006 to December 2009. Results Of the 306 patients with intracranial tumors, nosocomial infection occurred in 22 cases and the infection rate was 7.19%. The main infection was intracranial infection (46.15%), followed by incision infection (23.08%). Gram-negative bacteria were the main pathogens , Pseudomonas aeruginosa accounted for 23.81%. Conclusion The incidence of postoperative nosocomial infection in patients with intracranial tumors was significantly higher than that of other departments. The long operative time, invasive procedures, intraoperative implants and antimicrobial agents were the risk factors of nosocomial infection.