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目的:探讨H型高血压与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的相互关系。方法:选择2013年10月至2014年8月在上海市浦南医院心内科就诊的78例高血压住院患者,血浆同型半胱氨酸(Hcy)水平≥10μmol/L为H型高血压、血浆Hcy水平<10μmol/L为单纯性高血压。两者分别用便携式睡眠监测仪(PMD)检测,比较两组结果的差异。结果:H型高血压组的呼吸暂停低通气指数(AHI)高于单纯性高血压组(P<0.05),H型高血压组的OSAHS发病率与单纯组无差异(P>0.05),在有OSAHS的高血压病人中,H型高血压组有较高的中重度OSAHS的发病率(P<0.01)。结论:在高血压患者中,没有发现血浆Hcy水平与OSAHS相关。但是一旦存在OSAHS,则合并H型高血压患者中出现中重度OSAHS的概率较高。
Objective: To investigate the relationship between Hypertension and obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: From October 2013 to August 2014, 78 patients with hypertension in the Department of Cardiology, Punan Hospital of Shanghai were enrolled. The plasma homocysteine (Hcy) level was ≥10μmol / L as Hypertension and Hcy Level <10μmol / L for simple hypertension. Both were detected with a portable sleep monitor (PMD), comparing the differences between the two groups. Results: The apnea hypopnea index (HHI) of Hypertension group was higher than that of Hypertension group (P <0.05). The incidence of OSAHS in Hypertension group was not significantly different from that of Hypertension group (P> 0.05) Hypertension patients with OSAHS had a higher incidence of moderate-to-severe OSAHS (P <0.01). Conclusions: No plasma Hcy levels are associated with OSAHS in hypertensive patients. However, once OSAHS is present, there is a higher probability of developing moderate-to-severe OSAHS in patients with Hypertension.