含铜IUD的使用已愈20年,目前,国内外研制并使用的含铜IUD多为裸铜IUD,即铜丝或铜套位于IUD表面。本所研制的含铜宫腔形IUD(简称宫铜器)为内置铜IUD, 即铜丝在不锈钢宫形器的螺旋腔内。经大量的临床应用,避孕效果与其它裸铜IUD一致(失败率6.57/每100妇女)。本实验旨在比较裸铜与内置铜IUD对家兔子宫内膜形态学的影响,以期为内置铜IUD的长期安全性提供依据。 The use of copper-containing IUDs has been more than 20 years. At present, most of the copper-containing IUDs developed and used at home and abroad are bare copper IUDs, that is, copper wires or copper sleeves are located on the IUD surface. The copper-containing intrauterine shaped IUD developed by our institute is built-in copper IUD, that is, the copper wire is in the spiral cavity of a stainless steel pyramid. After extensive clinical application, the contraceptive effect was consistent with other bare copper IUDs (failure rate 6.57 / 100 women). The purpose of this experiment was to compare the effects of bare copper with built-in copper IUD on the endometrial morphology in rabbits in order to provide a basis for the long-term safety of the built-in copper IUD.