论文部分内容阅读
本文观察8例尿毒症患者,在应用 CAPD 进行治疗过程中,为预防腹膜炎的发生,而在腹透液中分别加入不同剂量的庆大霉素。根据用药方式的不同分成六组,同时应用“微量微生物法”进行庆大霉素血药浓度的监测。结果说明单纯为了预防感染而用庆大霉素是不必要的。虽然小剂量但长期应用、亦会加重肾功衰竭和第八颅神经的损害,应引起极大重视。对刚开始腹透治疗或有感染可能的患者,进行预防性治疗,则提倡早晚二次给药、每次四万。这样做即安全有效,而且又能节约用药。
In this paper, 8 cases of uremic patients observed in the application of CAPD for the treatment process, in order to prevent the occurrence of peritonitis, and in the peritoneal dialysis were added different doses of gentamicin. Divided into six groups according to different modes of administration, at the same time the application of “Microbiological Method” for the monitoring of gentamicin plasma concentration. The results suggest that gentamicin alone is not necessary to prevent infection. Although low-dose but long-term application, will also increase the renal failure and cranial nerve damage, should cause great attention. For patients who have just started transperitoneal dialysis or are likely to have an infection, prophylactic treatment is recommended for twice-daily and twice-daily doses of 40,000 each. This is safe and effective, but also saves medication.