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采用脑脊液聚合酶链反应(PCR)与抗结核抗体酶联免疫吸附试验(ELISA)观察结核性脑膜炎32例,对照组30例,以评价两种技术的诊断价值。结果显示:PCR与ELISA单独应用时其敏感性及特异性无明显差异(P>0.05),二者作平行试验时其敏感性高达96.88%,明显高于两者单独应用,特异性和准确性较单独应用时差异无显著性。提示:PCR是诊断结核性脑膜炎较有前途的技术,PCR与ELISA的平行试验具有互补作用。
32 cases of tuberculous meningitis and 30 cases of control group were observed by polymerase chain reaction (PCR) and anti-TB antibody ELISA. The diagnostic value of these two techniques was evaluated. The results showed that the sensitivity and specificity of PCR and ELISA alone were not significantly different (P> 0.05). The sensitivity of the two assays was 96.88% when compared with ELISA alone, which was significantly higher than that of the other two There was no significant difference in sex and accuracy when applied alone. Tip: PCR is a more promising technique for the diagnosis of tuberculous meningitis. PCR and ELISA parallel experiments have complementary effects.