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应用ELISA法测定42例囊虫病人用吡喹酮治疗前血清、脑脊液和治疗后2个月血清IgG、IgM和IgA。结果显示:治疗前血清特异性抗体阳性率分别为IgG95.23%,IgM92.85%和IgA90.47%;治疗后2个月分别为IgG95.23%,IgM92.85%,IgA88.09%。治疗前后三种血清抗体比较无显著性差异(P>0.05)。治疗前脑脊液抗体分别为IgG85.71%,IgM95.23%和IgA92.85%。提示:囊虫可溶性抗原可刺激B淋巴细胞产生IgG、IgM和IgA特异性抗体,诱发抗体介导的免疫反应。
Serum IgG, IgM and IgA levels in serum and cerebrospinal fluid of 42 patients with cysticercosis before and after treatment with praziquantel and 2 months after treatment were measured by ELISA. The results showed that the positive rates of serum specific antibodies before treatment were respectively IgG95.23%, IgM92.85% and IgA90.47%; two months after treatment, IgG95.23%, IgM92.85% and IgA88.09% respectively. There was no significant difference between the three serum antibodies before and after treatment (P> 0.05). Before treatment CSF antibodies were IgG85.71%, IgM95.23% and IgA92.85%. Tip: Cysticercus soluble antigen can stimulate B lymphocytes produce IgG, IgM and IgA specific antibodies, induced antibody-mediated immune response.