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作者对日本福罔九州大学医院第二外科部在1965年～1987年期间接受胃切除手术治疗的423例早期胃癌患者进行长期随访,并就其临床病理学特征和预后与同期接受手术的1196例进展期胃癌作对照分析.全组病例均根据日本外科学和病理学胃癌研究常 规对切除的胃癌标本进行病理学诊断和分类.早期胃癌只限胃部病变侵犯的深度在粘膜层或粘膜及粘膜下层.胃癌早期检出在日本多数医院在20～40%,早期胃癌病人五年生存率大于90%,而对照组仅30～60%.根据淋巴结清除范围的不同,将胃切除术分为R.(第一站淋巴结不完全切除)、R_1、R_2和R_3,术后一个月内,早期胃癌组死亡2例(0.5%),而进展期胃癌组死亡20例.用IBM 4381型计算机BMDP统计学分析,BMDP,P4F和P3S程序作卡方检验.用Mann Whitny试验将早期胃癌和进展期胃癌资料作对照分析,BMDP PIL程序Kaplan-Meier方法和Wilcoxon试验分析生存率和生存曲线.还用BMDP P2L程序和Cox回归分析法作多变量等校正.
The authors conducted a long-term follow-up of 423 patients with early gastric cancer who underwent gastrectomy during the period between 1965 and 1987 in the Second Department of Surgery, Kyushu University Hospital, Fukui, Japan, and their clinical pathological features, prognosis, and 1196 cases undergoing surgery during the same period. Advanced gastric cancer was used as a control analysis. All the cases were diagnosed and classified according to the pathology of gastric cancer in Japan. The early gastric cancer was limited to gastric mucosal lesions or mucous membranes and mucosa. Lower layers. Early detection of gastric cancer in most hospitals in Japan in 20 to 40%, five-year survival rate of early gastric cancer patients is greater than 90%, while the control group is only 30 to 60%. According to the scope of lymph node clearance, the gastrectomy is divided into R (Incomplete resection of first-site lymph nodes), R_1, R_2, and R_3, within one month after surgery, 2 patients (0.5%) died of early gastric cancer, while 20 patients died of advanced gastric cancer. BMDP statistics were calculated using IBM 4381 computer. Analysis, BMDP, P4F, and P3S procedures were used for chi-square test. Mann Whitny test was used to analyze the data of early gastric cancer and advanced gastric cancer. BMDP PIL program Kaplan-Meier method and Wilcoxon test were used to analyze survival rate and survival. Curve. BMDP P2L further correction and Cox regression analysis program variables long on.