新生血管是指原有微血管内皮细胞经过生芽、迁移、增殖与基质重塑等过程而产生的新血管,成年人生理性的新生血管仅见于月经期和哺乳期的女性生殖器官。近年来大量研究表明内膜新生血管是动脉粥样硬化疾病普遍存在的特征,它是动脉粥样硬化发生发展的重要危险因素,而且新生血管在不稳定性斑块及斑 Neovascularization refers to the generation of new blood vessels by the process of germination, migration, proliferation and matrix remodeling of the original microvascular endothelial cells. Physiological neovascularization is only found in female reproductive organs during menstruation and lactation. In recent years, a large number of studies have shown that endocardial neovascularization is a common feature of atherosclerotic disease, it is an important risk factor for the development of atherosclerosis, and angiogenesis in unstable plaques and plaques